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at TPLO rads

Let's take your
infection control to

the next level

Watch these videos!

(2) Hunter et al., “Clinical Effectiveness of a Biofilm Disrupting Surgical Lavage in Reducing Bacterial Contamination in Total Knee Arthroplasty Revision Surgery in Known Cases of Prosthetic Joint Infection”, Zimmer Biomet white paper. (administered 1 litre volume via pulsed jet lavage)

(3) O’Donnell J, Wu M, Cochrane N, Belay E, Myntti M, James G, Seyler T, “Efficacy of Common Antiseptic Solutions Against Clinically Relevant Planktonic Microorganisms,” Orthopedics (2022)

Step #1

Getting Ready

Step #1

Getting Ready

Ensuring a clean surgical field starts with proper skin preparation. This video demonstrates the best practices for:

Shaving the patient – Achieving a close, even shave while minimizing skin irritation
The Dirty Scrub – The initial skin prep step to remove surface debris and reduce bacterial load before the sterile scrub.

Following these techniques helps reduce infection risk and improve surgical outcomes. Watch the video to see how it’s done effectively!

Step #2

Reduce Your Risks

Step #2

Reduce Your Risks

Many surgeons are shocked to find out that their patients are not protected from biofilms and resistant bacteria when they use saline and post-op antibiotics.

That’s Where Simini Comes In.

Why leave these risks and unmanaged? Just apply Simini Protect Lavage for one minute. Biofilms and resistant bacteria can be removed, and you can reduce two significant sources of infection.

Protect Your Patients

Step #3

Take the Course

Step #3

Take the Course

Preventing surgical infections is critical for patient safety and successful outcomes. This course covers:

Aseptic techniques – Best practices to maintain a sterile field.
Skin prep & draping – Proper methods to minimize contamination.
Antibiotic stewardship – When and how to use perioperative antibiotics effectively.

Stay up to date with the latest evidence-based protocols. Click the link to start learning and earn CE credits!

Evidence Level #1

Bacteria removal with Simini

Evidence Level #1

Bacteria removal with Simini

Simini Protect Lavage has been evaluated in laboratory studies, clinical studies and case studies

In clinical and laboratory studies, Simini Protect Lavage removed 99.98% of bacteria (2), (3)

Key Fact: Laboratory studies with have shown Simini Protect Lavage removed 99.98% of bacteria whether biofilms were present or not
So Simini Protect Lavage can be broadly used across your orthopedic surgical caseload
Perfect complement to a multi-modal infection control protocol adding targeted removal of resistant bacteria and biofilms
Simini Protect Lavage is the identical fluid to Zimmer's Bactisure for human surgery

Start Your Free Trial Today

(3) O’Donnell J, Wu M, Cochrane N, Belay E, Myntti M, James G, Seyler T, “Efficacy of Common Antiseptic Solutions Against Clinically Relevant Planktonic Microorganisms,” Orthopedics (2022)

Evidence Level #2

Simini compared to saline

Evidence Level #2

Simini compared to saline

Texas Tech University

Murine surgical model after inoculation with

MRSA (Methicillin-resistant staph. aureus) or Pseudomonas Aeruginosa (5)

Simini demonstrates significant reduction in bacteria compared to saline

Sham surgery on a rodent's back
Inoculate with either MRSA or Pseudomonas and wait 40-60 minutes to simulate surgery time
Lavage the wound with saline, Simini or positive control
Excise tissue to count the number of bacteria present

Start Your Free Trial Today

Learn More About Websites →

(1) I. Forzisi, L. Vezzoni, M. Bozzerla, A.Vezzoni “Intraoperative Antiseptic Lavage with Simini for Prevention and for Treatment of SSI.” European Society of Veterinary Orthopaedics and Traumatology Meeting, Sept 24, 2022

Evidence Level #3

Simini compared to
povidone iodine and chlorhexidine

Evidence Level #3

Simini compared to
povidone iodine and chlorhexidine

Simini Protect Lavage demonstrated the overall greatest efficacy of all the agents studied.

Published independent studies

O'Donnell et al. compares planktonic bacteria removal (bacteria with no biofilms present) (3)
Kia et al. compares bacteria removal with biofilms present (4)
Evaluates removal of Staph Aureus, Pseudomonas and other bacteria
Simini Protect Lavage is the identical solution to Zimmer's Bactisure for human surgeons

Start Your Free Trial Today

(3) O’Donnell J, Wu M, Cochrane N, Belay E, Myntti M, James G, Seyler T, “Efficacy of Common Antiseptic Solutions Against Clinically Relevant Planktonic Microorganisms,” Orthopedics (2022)

(4) Kia C, Cusano A, Messina J, Muench LN, Chadayammuri V, McCarthy MB, Umejiego E, Mazzocca AD, “Effectiveness of topical adjuvants in reducing biofilm formation on orthopedic implants: an in vitro analysis”, Journal of Shoulder and Elbow Surgery (2021)

Evidence Level #4

Veterinary Clinical Study

Evidence Level #4

Veterinary Clinical Study

Study Design:

Patients were selected because they were at a high risk of infection or were revision cases, where an infection was present.

For each surgery, there was a swab to culture for bacteria just after the opening of the surgery. The procedure was then performed, and then just prior to suturing, the surgical wound was lavaged with Simini Protect Lavage. Following this lavage, a second swab was taken for analysis.

The patient was sutured, and follow-up occurred for all patients 6 months following the study.

Study Conclusion

According to the experience of the authors, Simini Protect Lavage was a highly effective medical device, that allowed the prevention of infection in surgeries with higher risk of infection and moreover it allowed for the eradication of infections without the need to remove implants when performing surgical revisions in a single stage.

Start Your Free Trial Today

Learn More About Websites →

Evidence Level #5

Human Clinical Study

Evidence Level #5

Human Clinical Study

Study Design:

A human clinical study was performed in 45 patients with a total knee replacement and a periprosthetic joint infection.

During the revision surgery, just prior to closing, a sample was taken from the surgical wound, the wound was lavaged with Simini Protect Lavage, and then a subsequent sample was taken thereafter.

These patients were then followed-up at 3 months post surgery which is consistent with W.H.O. guidelines.

Results:

Application of the Simini Protect Lavage demonstrated a 99.98% removal of bacteria in the wound
90 Day post-surgery infection rate was observed to be 38% lower than historical controls

Start Your Free Trial Today

Safety Studies

Completed safety studies required for human medical device clearance (6),(7)
Successful studies have demonstrated Simini Protect Lavage compatibility with orthopedic implants and materials

Start Your Free Trial Today

Still not convinced...

Review veterinary case studies
with Simini Protect Lavage

In these studies,
Simini Protect Lavage
has been tested

by veterinary surgeons

in tough clinical situations

to give you the confidence

of its benefit

across your surgical practice

In these studies, Simini Protect Lavage
has been tested by veterinary surgeons

in tough clinical situations

to give you the confidence

of its benefit across your surgical practice

Start Your Free Trial Today

Get Started In Less Than 60 Seconds

Veterinary Case Studies

Start Your Free Trial Today

Orthopedic Surgeries
Emergency Procedures
Fracture Repair
Wounds

Not sure where to use Simini

Simini Protect Lavage can be used for most types of surgical orthopedic procedures.
Simini Protect Lavage cannot be used in the eyes and ears, abdomen and thorax.

Orthopedic Surgeries
Emergency Procedures
Fracture Repair
Wounds

Biofilms, Bacteria & Simini

Biofilms form quickly: In as little as 20 minutes (less than the time for an average TPLO procedure)
Bacteria more resistant: Up to 1000X more resistant when in biofilm
Removed 99.98% of bacteria: Clinical trial result with Simini Protect Lavage fluid (1)

Proudly show how you are a
"Sustainable Vet"

Demonstrate to clients how you provide addition protection for their pet by using Simini Protect Lavage
How using non-antibiotic Simini Protect Lavage is an important step for responsible antibiotics use
Clients value products that protect their pet, while protecting human medicines in a sustainable way

Sign up for a free wall posterof all the TPLO Rad Steps

Let's take yourinfection control to the next level

Step #1

Getting Ready

Step #1

Getting Ready

Ensuring a clean surgical field starts with proper skin preparation. This video demonstrates the best practices for:

Following these techniques helps reduce infection risk and improve surgical outcomes. Watch the video to see how it’s done effectively!

Step #2

Reduce Your Risks

Step #2

Reduce Your Risks

Many surgeons are shocked to find out that their patients are not protected from biofilms and resistant bacteria when they use saline and post-op antibiotics.

That’s Where Simini Comes In.

Why leave these risks and unmanaged? Just apply Simini Protect Lavage for one minute. Biofilms and resistant bacteria can be removed, and you can reduce two significant sources of infection.

Step #3

Take the Course

Step #3

Take the Course

Preventing surgical infections is critical for patient safety and successful outcomes. This course covers:

Stay up to date with the latest evidence-based protocols. Click the link to start learning and earn CE credits!

Evidence Level #1

Bacteria removal with Simini

Evidence Level #1

Bacteria removal with Simini

Simini Protect Lavage has been evaluated in laboratory studies, clinical studies and case studies

In clinical and laboratory studies, Simini Protect Lavage removed 99.98% of bacteria (2), (3)

Evidence Level #2

Simini compared to saline

Evidence Level #2

Simini compared to saline

Texas Tech University Murine surgical model after inoculation with MRSA (Methicillin-resistant staph. aureus) or Pseudomonas Aeruginosa (5)

Simini demonstrates significant reduction in bacteria compared to saline

Learn More About Websites →

Evidence Level #3

Simini compared to povidone iodine and chlorhexidine

Evidence Level #3

Simini compared to povidone iodine and chlorhexidine

Simini Protect Lavage demonstrated the overall greatest efficacy of all the agents studied.

Published independent studies

Evidence Level #4

Veterinary Clinical Study

Evidence Level #4

Veterinary Clinical Study

Study Conclusion

Learn More About Websites →

Evidence Level #5

Human Clinical Study

Evidence Level #5

Human Clinical Study

Results:

Safety Studies

Safety Studies

Review veterinary case studies with Simini Protect Lavage

In these studies, Simini Protect Lavage has been tested by veterinary surgeons in tough clinical situations to give you the confidence of its benefit across your surgical practice

In these studies, Simini Protect Lavage has been tested by veterinary surgeons in tough clinical situations to give you the confidence of its benefit across your surgical practice

Veterinary Case Studies

Not sure where to use Simini

Biofilms, Bacteria & Simini

Proudly show how you are a "Sustainable Vet"

Simini Technologies Product. All Rights Reserved © 2021-2024. 103 Sato Street, Whitby Ontario L1R 1V8.

Working...

Sign up for a free wall poster
of all the TPLO Rad Steps

Let's take your
infection control to

the next level

Texas Tech University

Murine surgical model after inoculation with

MRSA (Methicillin-resistant staph. aureus) or Pseudomonas Aeruginosa (5)

Simini compared to
povidone iodine and chlorhexidine

Simini compared to
povidone iodine and chlorhexidine

Review veterinary case studies
with Simini Protect Lavage

In these studies,
Simini Protect Lavage
has been tested

by veterinary surgeons

in tough clinical situations

to give you the confidence

of its benefit

across your surgical practice

In these studies, Simini Protect Lavage
has been tested by veterinary surgeons

in tough clinical situations

to give you the confidence

of its benefit across your surgical practice

Proudly show how you are a
"Sustainable Vet"

Simini Technologies Product.

All Rights Reserved © 2021-2024.

103 Sato Street, Whitby Ontario L1R 1V8.